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Amoeba Parasite

Scientists Create Immunity to Deadly Parasite by Manipulating Host’s Genes

Original Source: There are two common approaches to protecting humans from infectious disease: targeting pathogens and parasites with medicines such as antibiotics, or dealing with the conditions that allow transmission. Now exciting new research from the University of Virginia School of Medicine and the University of Colorado demonstrates the effectiveness of a third strategy: adjusting the landscape of the human body to remove the mechanism that allows pathogens to cause disease. The researchers have silenced genes within human cells to induce immunity to the parasite E. histolytica, which infects 50 million people and causes 40,000 to 110,000 deaths worldwide each year via severe diarrhea. “This amoeba is a cluster bomb – a voracious killer,” said U.Va.’s Chelsea Marie, a research scientist in infectious diseases and international health,...